-Has been performing in a show called "Communicating Doors" in New York City at the Variety Theatre on Third Avenue.

-Is part Swedish.

-Been performing in "Proof" at Manhattan Theatre Club, which is currently being moved to Broadway (Dec. 2000)

-She is currently living with boyfriend and fellow actor, Billy Crudup. They met when they did the critically drubbed revival of "Bus Stop" in 1996.

-Dated actor Timothy Hutton when they did the play "Prelude to a Kiss" together off Broadway in 1991.

-Won the Tony for Best Actress in a Play for "Proof" (2001)

-The Counting Crows song "Butterfly in Reverse" was written for her.

"Weeds" (2005) TV Series (filming) .... Nancy Botwin
Romance & Cigarettes (2005) (completed) .... Constance
Vinegar Hill (2005) (TV) .... Ellen Grier
Miracle Run (2004) (TV) .... Corrine Morgan-Thomas
Saved! (2004) .... Lillian
The Best Thief in the World (2004) .... Sue
Angels in America (2003) (TV) .... Harper Pitt
Saved (2003)
"Master Spy: The Robert Hanssen Story" (2002) (mini) TV Series .... Bonnie Hanssen
Red Dragon (2002) .... Molly Graham
Pipe Dream (2002) .... Toni Edelman
"West Wing, The" (1999) TV Series .... Amy Gardner (2001- )
Cupid & Cate (2000) (TV) .... Cate DeAngelo
Let the Devil Wear Black (1999) .... Julia Hirsch
Five Senses, The (1999) .... Rona
Simple Life of Noah Dearborn, The (1999) (TV) .... Dr. Valerie Crane
Goodbye Lover (1999) .... Peggy Blane
Saint Maybe (1998) (TV) .... Lucy Ann Deen-Dulcimer-Bedloe
Legalese (1998) (TV) .... Rica Martin
Murder in Mind (1997/I) .... Caroline Walker
Maker, The (1997) .... Officer Emily Peck
Portrait of a Lady, The (1996) .... Henrietta Stackpole
Sugartime (1995) (TV) .... Phyllis McGuire
Reckless (1995/I) .... Pooty
Boys on the Side (1995) .... Robin
Bullets Over Broadway (1994) .... Ellen
Client, The (1994) .... Dianne Sway
Place for Annie, A (1994) (TV) .... Linda
Naked in New York (1994) .... Joanne White
Mr. Wonderful (1993) .... Rita
Fried Green Tomatoes (1991) .... Ruth Jameson
Grand Canyon (1991) .... Dee
Longtime Companion (1990) .... Lisa
Signs of Life (1989)(as Mary Louise Parker) .... Charlotte
Too Young the Hero (1988) (TV) .... Pearl Spencer
"Ryan's Hope" (1975) TV Series